Cold Spring Harbor Laboratory

Cold Spring Harbor LaboratoryRequisition InformationRequisition TitleScientific Admin AsstPosition CategoryAdministrative/ClericalRequisition Number01316-AOpening InformationJob StatusFull TimeEducation RequiredAssociates DegreePosition DescriptionCold Spring Harbor Laboratory ( CSHL ), a world-renowned biomedical research facility on Long Island's North Shore, is searching for a Scientific Administrative Assistant to provide administrative support to a group of faculty and their lab staff at the CSHL Genome Center. This exciting opportunity covers a range of responsibilities related to supporting the administrative needs of a scientific laboratory. These include: assisting faculty members in the preparation and submission of federal grants and other funding opportunities; preparation of grant progress reports and scientific publications; assisting with oversight of laboratory expenses and budgets; scheduling meetings and appointments; maintaining calendars; making travel arrangements and reimbursements; and updating websites, Other responsibilities could include preparing schedules for visiting seminar speakers, assisting in organizing weekly seminars and ordering supplies.Position RequirementsEducation: An Associate's degree is required and a Bachelor's degree is preferred. Experience: The ideal candidate will possess a minimum of four to five years of related experience. Experience with submission of federal grants and familiarity with scientific terminology preferred. Skills: This individual must have strong organizational, communication and PC skills, including MS Word, Excel, Powerpoint and Outlook (familiarity with Mac OS X, Canvas, FileMaker Pro and Endnote are desired but not required). Must be able to multi-task with good time management skills and thrive under pressure. Please apply for the position via the CSHL careers website at: http://cshl.peopleadmin.com/postings/14989 Position Number: 01316-A Founded in 1890, CSHL has helped shape contemporary biomedical research and education with today's research endeavors encompassing cancer, neuroscience, plant biology and quantitative biology. CSHL is a private, not-for-profit institution in New York and has been home to eight Nobel Prize winners. Today, CSHL's multidisciplinary scientific community is bolstered by more than 600 researchers and its Scientific Meetings & Courses Program, which hosts more than 9,000 scientists from around the world each year on its campus. For more information about CSHL , please visit us at www.cshl.edu. CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability or protected veteran status. VEVRAA Federal ContractorPI107805406

Cold Spring Harbor LaboratoryRequisition InformationRequisition TitleResearch Technician IPosition CategoryScience/Research (RSCH)Requisition Number02293-ROpening InformationJob StatusFull TimeEducation RequiredUndergraduate DegreeExperience RequiredLess than 1 yearPosition DescriptionHoward Hughes Medical Institute ( HHMI ) is a science philanthropy whose mission is to advance biomedical research and science education for the benefit of humanity. We empower exceptional scientists and students to pursue fundament questions about living systems, and work to share scientific discoveries with researchers, students and science-curious individuals around the world. Founded in 1953 by aviator and industrialist Howard R. Hughes, HHMI is headquartered in Chevy Chase, Maryland, and employs more than 2500 people across the U.S. Visit hhmi.org/careers to learn more about working at HHMI . CSHL is seeking a Research Technician to study the protein components of the RNAi machinery in cells, which can selectively silence genes, as well as complexes involved in DNA replication in Dr. Leemor Joshua-Tor's laboratory at Cold Spring Harbor Laboratory in Cold Spring Harbor, NY. Under general supervision, the Research Technician will assist scientists in the performance of laboratory and investigative procedures by performing a variety of routine experimental techniques such as cloning, gel electrophoresis, PCR , centrifugation, chromatography, and the like. The Research Technician will collect, verify, record, and compile data and information in support of research. Preference for candidates that have demonstrated experience in protein expression and purification.Position Requirements- Bachelor of Science degree in biology or relevant field of science or technology required. Master's degree and 1 year of experience preferred. -Assist scientists by performing various investigative procedures and operating a variety of instruments and other scientific equipment. -Collect, record, organize and verify the accuracy of data; perform calculations and prepare charts, graphs and reports. May use software applications to assemble, manipulate and/or format data and test reports. -Configure and operate laboratory apparatus and instruments; read and record instrument data; tabulate data; keep laboratory records. -May order chemicals, reagents, and other laboratory supplies. -Participate in laboratory meetings and planning sessions. -May maintain insects, plants, animals and/or bacterial and tissue cultures for experimental purposes. -Read literature applicable to research areas as required. -Perform the duties of a Laboratory Assistant as required. If interested, please apply for this position via the CSHL Careers website at: http://cshl.peopleadmin.com/postings/14774 Position Number: 02293-R Please include a cover letter and three references with your resume. We offer a competitive salary and comprehensive benefits package. Cold Spring Harbor Laboratory is a world-renowned research and educational institution with programs in cancer, neuroscience, plant biology, genomics and bioinformatics. The Laboratory is recognized internationally for its excellence in research and educational activities. For more information about CSHL , please visit us at www.cshl.edu. PI106963152

Cold Spring Harbor LaboratoryRequisition InformationRequisition TitleEducational Grants AssistantPosition CategoryAdministrative/ClericalRequisition Number01286-AOpening InformationJob StatusPart Time (No Benefits)Education RequiredAssociates DegreeExperience Required1 - 3 YearsPosition DescriptionCold Spring Harbor Laboratory is presently seeking an Educational Grants Assistant to provide administrative support to the Director, Finance and Educational Grants in the Meetings and Courses office. This position is a part-time position with potential to increase in hours. Responsibilities include but are not limited to: - Provide Administrative support to Director, Finance & Educational Grants. - Review and process travel vouchers for the Meeting and Course Program and the Banbury Center. - Assist in monitoring spending on all grants so that grants are neither overspent nor significantly under spent. - Assist with post-award administration of grants to ensure proper spending - Open accounts in Lawson per A/P & Purchasing requests. - Maintain funding list for Meeting Program and Course Program. - Assist in preparation of materials to prepare grant application to support meetings and courses - Assist in preparing and gathering information for progress and final reports due annually to federal agencies, industries and foundations - Other duties as assignedPosition RequirementsThis is an entry level position and a great opportunity to gain experience in an office setting, with a focus on grants management and accounting. Some customer service and office experience a plus. A bachelor's degree is preferred. Knowledge of excel and word, knowledge of Lawson Business system a plus. Must have use of a personal vehicle. If interested, please apply for this position via the CSHL website using this link: http://cshl.peopleadmin.com/postings/14793 Position number: 01286-A For more information about CSHL , please visit us at www.cshl.edu. CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status. VEVRAA Federal Contractor. PI106774721

Cold Spring Harbor LaboratoryRequisition InformationRequisition TitlePostdoctoral FellowPosition CategoryPost DoctoralRequisition Number02318-ROpening InformationJob StatusFull TimeEducation RequiredGraduate DegreeExperience RequiredLess than 1 yearPosition DescriptionDr. Lingbo Zhang's Lab at Cold Spring Harbor Laboratory is seeking postdoctoral fellow to develop novel therapeutics for various forms of devastating hematopoietic malignancy. The Zhang Lab is interested in understanding how self-renewal of hematopoietic stem and progenitor cell is regulated under both normal and malignant conditions and how dysregulation of self-renewal process contributes to pathogenesis of various hematopoietic malignancies. The Lab is addressing these questions through both CRISPR /Cas functional and chemical genomic approaches to identify novel self-renewal regulators and metabolic vulnerabilities and to ultimately develop chemical probes to target these molecular events as novel therapeutics for hematopoietic malignancies. The Lab has recently identified multiple promising drug targets to treat hematopoietic malignancies including myelodysplastic syndrome and acute leukemia. A clinical trial based on one of these drug targets to treat drug-refractory myelodysplastic syndrome is currently under preparation. The Lab is now seeking outstanding candidate to functionally characterize drug targets and identify molecular markers that predict responsiveness to these novel therapeutics. The ultimate goal is to develop novel therapeutics for various forms of devastating hematopoietic malignancy. Cold Spring Harbor Laboratory is a world-renowned biomedical research institution in New York. It has shaped contemporary biomedical research and is the home of eight Nobel Prize laureates. Cold Spring Harbor Laboratory provides a highly dynamic and interactive research environment and also a unique opportunity of timely exposure to advances in various biomedical research fields and of interaction with a broad range of researchers from all over the world through its renowned Meetings and Courses program.Position RequirementsCandidates should hold a graduate degree (PhD, MD or equivalent) in biomedical fields. Interested candidates should send cover letter, CV, research statement (including research accomplished during PhD and research expected to work on during postdoctoral fellowship), and 3 contacts for reference to lbzhang@cshl.edu as well as online application found here: http://cshl.peopleadmin.com/postings/14939 Cold Spring Harbor Laboratory offers a highly collaborative social and scientific environment as well as a competitive salary and benefits in a beautiful location about one hour from New York City. Position Number: 02318-R CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status.PI107611036

Cold Spring Harbor LaboratoryRequisition InformationRequisition TitleResearch Technician IPosition CategoryScience/ResearchRequisition Number02268-ROpening InformationJob StatusFull TimeEducation RequiredUndergraduate DegreeExperience RequiredLess than 1 yearPosition DescriptionCold Spring Harbor laboratory located on the North Shore of Long Island, is currently accepting applications for a Research Technician position in molecular biology. The successful candidate will participate in basic research on an exciting project at the intersection of neuroscience and molecular biology. Primary responsibilities involve DNA / RNA manipulation, including DNA and RNA isolation, cloning and PCR . Experience with high-throughput DNA sequencing technologies will be beneficial. The position requires great attention to detail, excellent organizational skills, the ability to troubleshoot and work independently, and a strong work ethic. The successful candidate will work as part of a larger team and should have good communication skills.Position RequirementsEducation & Experience: A Bachelor Degree in molecular biology or biotechnology, and at least 6 months of work experience is required for this position. An interest in neuroscience is preferred. Other Experience & Skills: Experience with RNA handling, and cell culture will be preferred. We offer a competitive salary & comprehensive benefits package. For immediate consideration, please apply online to the position found here: http://cshl.peopleadmin.com/postings/14609 Posting ID: 02268-R Founded in 1890, CSHL has helped shape contemporary biomedical research and education with today's research endeavors encompassing cancer, neuroscience, plant biology and quantitative biology. CSHL is a private, not-for-profit institution in New York and has been home to eight Nobel Prize winners. Today, CSHL's multidisciplinary scientific community is bolstered by more than 600 researchers and its Scientific Meetings & Courses Program, which hosts more than 9,000 scientists from around the world each year on its campus. For more information about CSHL , please visit us at www.cshl.edu CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status. PI106691627

Cold Spring Harbor LaboratoryRequisition InformationRequisition TitleLab Technician I ,AnimalPosition CategoryLab Animal ResourcesRequisition Number01307-AOpening InformationJob StatusFull TimeEducation RequiredAssociates DegreeExperience RequiredLess than 1 yearPosition DescriptionCold Spring Harbor Laboratory ( CSHL ), a world-renowned scientific research organization on Long Island's North Shore, is seeking responsible individuals to handle and care for small research animals under the direction of animal facility staff. Technicians will also provide general laboratory and animal nursing services to investigators and research technicians in laboratory animal techniques, and in accordance with detailed instructions and schedules. This includes animal husbandry, cage changing and providing a sanitary research environment.Position RequirementsEducation: An Associate's degree in a related discipline is required. Experience: At least six months of relevant work experience is preferred. Skills: Strong attention to detail and quality control are required. Time management skills and effective oral and written communication skills are also required. Must be able to operate cage washers, autoclaves, and other disinfecting/sterilizing equipment. Must be able to work with or around laboratory animals. Physical: Must be physically capable of lifting 50 pounds. Other: Occasional weekend/holiday work and a valid driver's license are required. Please apply for this position via the CSHL careers website at: http://cshl.peopleadmin.com/postings/14897 Position Number: 01307-A We offer a competitive salary and a comprehensive benefits package. For more information about CSHL , please visit us at www.cshl.edu CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status. VEVRAA Federal ContractorPI107524977

Cold Spring Harbor LaboratoryRequisition InformationRequisition TitleLab Technician I ,AnimalPosition CategoryLab Animal ResourcesRequisition Number01309-AOpening InformationJob StatusFull TimeEducation RequiredAssociates DegreeExperience RequiredLess than 1 yearPosition DescriptionCold Spring Harbor Laboratory ( CSHL ), a world-renowned scientific research organization on Long Island's North Shore, is seeking responsible individuals to handle and care for small research animals under the direction of animal facility staff. Technicians will also provide general laboratory and animal nursing services to investigators and research technicians in laboratory animal techniques, and in accordance with detailed instructions and schedules. This includes animal husbandry, cage changing and providing a sanitary research environment.Position RequirementsEducation: An Associate's degree in a related discipline is required. Experience: At least six months of relevant work experience is preferred. Skills: Strong attention to detail and quality control are required. Time management skills and effective oral and written communication skills are also required. Must be able to operate cage washers, autoclaves, and other disinfecting/sterilizing equipment. Must be able to work with or around laboratory animals. Physical: Must be physically capable of lifting 50 pounds. Other: Occasional weekend/holiday work and a valid driver's license are required. Please apply for this position via the CSHL careers website at: http://cshl.peopleadmin.com/postings/14916 Position Number 01309-A We offer a competitive salary and a comprehensive benefits package. For more information about CSHL , please visit us at www.cshl.edu CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status. VEVRAA Federal ContractorPI107524956

Cold Spring Harbor LaboratoryRequisition InformationRequisition TitleCage Washer TechnicianPosition CategoryLab Animal ResourcesRequisition Number01308-AOpening InformationJob StatusFull TimeEducation RequiredHigh SchoolExperience RequiredNonePosition DescriptionCold Spring Harbor Laboratory, a world-renowned research and educational organization, is seeking an individual for the position of Cage Washer Technician to uphold strict animal facilities sanitary guidelines and perform daily activities to maintain a clean laboratory environment throughout the facility. Responsibilities include: - Following detailed instructions from the Animal Facility Manager - Cleaning cages, feeding equipment and animal rooms - Using disinfectant spray and mopping floors and walls - Operating equipment to disinfect/sterilize - Performing cage washer and autoclave quality assurance The ideal person will concentrate on routine tasks and perform activities to ensure proper disinfection of the animal laboratory facilities on a daily basis. Being able to work with or around laboratory animals is a must.Position RequirementsEducation: High school or equivalent. Experience: Experience working with or around laboratory animals is preferred. Physical: Must be able to lift and carry fifty pounds. This position requires standing most of the day. Environmental: Must feel comfortable working around laboratory animals and in areas with elevated environmental noise levels. Other requirements: Must have a valid driver's license; use of personal vehicle required. Ability to work occasional overtime, weekends and holidays. Please apply for this position via the CSHL careers website at: http://cshl.peopleadmin.com/postings/14899 Position Number: 01308-A We offer a competitive salary and a comprehensive benefits package. For more information about CSHL , please visit us at www.cshl.edu CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status. VEVRAA Federal ContractorPI107524936

Cold Spring Harbor LaboratoryRequisition InformationRequisition TitlePostdoctoral FellowPosition CategoryPost DoctoralRequisition Number02313-ROpening InformationJob StatusFull TimeEducation RequiredGraduate DegreeExperience RequiredLess than 1 yearPosition DescriptionThe Yeh Laboratory at CSHL Cancer Center (http://yehlab.labsites.cshl.edu) is seeking for a postdoctoral fellow to work on immuno-oncology and antibody discovery projects. Our lab is working to understand the mechanisms to efficiently elicit tumor immunogenicity for potent cancer immunotherapy development. The postdoc will be responsible of employing and developing NGS , single cell and display library methods to study cancer immunotherapy and therapeutic antibody discovery (in animal models and in human clinical trial studies). Experience in tumor infiltrating lymphocyte manipulation and analysis is highly desirable. The Yeh Lab is a highly-collaborative environment with state of the art facilities and expertise in biotherapeutics engineering. This postdoctoral fellow will take responsibility of conducting independent research as well as collaborating with other members in the group. The Yeh Lab also engages in several close collaborations with other research groups at the Cancer Center. The postdoctoral fellow will enjoy the highly intellectual and collaborative interactions at CSHL .Position RequirementsQualified candidate should have a doctorate degree (PhD, MD or equivalent) in the field of biology, chemistry or chemical and biological engineering. Graduate students expecting to complete their doctoral studies within the next 8 months are also welcome to apply. The candidates need to demonstrate good working ethic and personal skills working independently as well as within a team. Interested applicants should submit an application here: http://cshl.peopleadmin.com/postings/14905 in addition to emailing a Cover Letter, CV (with the contacts of three referees) and a brief Scientific Interests to jyeh@cshl.edu. Cold Spring Harbor Laboratory offers a highly collaborative social and scientific environment as well as a competitive salary and benefits in a beautiful location about one hour from New York City. CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status.PI107483309

Cold Spring Harbor LaboratoryRequisition InformationRequisition TitleResearch Technician IPosition CategoryScience/ResearchRequisition Number02286-ROpening InformationJob StatusFull TimeEducation RequiredUndergraduate DegreeExperience RequiredLess than 1 yearPosition DescriptionCold Spring Harbor Laboratory is seeking a highly motivated and responsible candidate for a research assistant position opening in January 2019 in the Schorn laboratory. Mobile DNA has contributed to a large fraction of our DNA and is still active in many organisms. The Schorn lab is interested in mechanisms of small RNA -mediated transposon control, especially by tRNA-derived fragments that are abundant in stem cells and cancer cell lines. These tRNA fragments are processed from the 3'-end of full-length tRNAs under yet unknown conditions and protect many cell types in eukaryotes by inhibiting LTR -retrotransposons and -retroviruses. The ideal candidate will be trained in basic molecular biology practices including cloning, plasmid construction, DNA / RNA extractions, PCR , and sterile working. Responsibilities will include tissue/cell culture work, setting up a new lab space, general laboratory organization, and maintenance of laboratory supplies.Position RequirementsEDUCATION : Bachelor's Degree in Biological or Chemical Sciences is required. EXPERIENCE : 1 to 2 years of experience working in a laboratory is preferred. Experience with mammalian cell culture is a plus, including sterile technique, splitting cells, preparing sterile culture media and solutions. SKILLS / OTHER : Strong skills in laboratory record keeping and attention to detail are important. Candidate should have excellent communication skills, solid analytical & organizational ability. To be considered candidates must also apply for this position via the CSHL website at: http://cshl.peopleadmin.com/postings/14743 Position Number: 02286-R Cold Spring Harbor Laboratory offers a highly collaborative social and scientific environment as well as a competitive salary and benefits. CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status. VEVRAA Federal Contractor PI106641070

Cold Spring Harbor LaboratoryRequisition InformationRequisition TitleScientific Administrative AssistantPosition CategoryAdministrative/ClericalRequisition Number01270-AOpening InformationJob StatusFull TimeEducation RequiredExperience RequiredPosition DescriptionCold Spring Harbor Laboratory ( CSHL ), a world-renowned biomedical research facility on Long Island's North Shore, is searching for a Scientific Administrative Assistant to provide administrative support to a group of faculty and their lab staff at CSHL . This exciting opportunity covers a range of responsibilities related to supporting the administrative needs of a scientific laboratory. These include: assisting faculty members in the preparation and submission of federal grants and other funding opportunities; preparation of grant progress reports and scientific publications; assisting with oversight of laboratory expenses and budgets; scheduling meetings and appointments; maintaining calendars; making travel arrangements and reimbursements; and updating websites, Other responsibilities could include preparing schedules for visiting seminar speakers, assisting in organizing weekly seminars and ordering supplies.Position RequirementsEducation: An Associate's degree is required and a Bachelor's degree is preferred. Experience: The ideal candidate will possess a minimum of four to five years of related experience. Experience with submission of federal grants and familiarity with scientific terminology preferred. Skills: This individual must have strong organizational, communication and PC skills, including MS Word, Excel, Powerpoint and Outlook (familiarity with Mac OS X, Canvas, FileMaker Pro and Endnote are desired but not required). Must be able to multi-task with good time management skills and thrive under pressure. Please apply for the position via the CSHL careers website at: http://cshl.peopleadmin.com/postings/14719 Position Number: 01270-A Founded in 1890, CSHL has helped shape contemporary biomedical research and education with today's research endeavors encompassing cancer, neuroscience, plant biology and quantitative biology. CSHL is a private, not-for-profit institution in New York and has been home to eight Nobel Prize winners. Today, CSHL's multidisciplinary scientific community is bolstered by more than 600 researchers and its Scientific Meetings & Courses Program, which hosts more than 9,000 scientists from around the world each year on its campus. For more information about CSHL , please visit us at www.cshl.edu. CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability or protected veteran status. VEVRAA Federal Contractor PI106641032

Cold Spring Harbor LaboratoryRequisition InformationRequisition TitleComputational Science Developer IPosition CategoryScience/ResearchRequisition Number02263-ROpening InformationJob StatusFull TimeEducation RequiredUndergraduate DegreeExperience Required1 - 3 YearsPosition DescriptionCold Spring Harbor Laboratory invites applications for a Computational Science Developer I in the laboratory of Dr. Alexander Dobin. The successful candidates will join a team of biological data scientists working on novel statistical methods and computational algorithms for multi-omics processing and integration, and leverage Big Genomic Data to elucidate various problems in precision health, such as genetic and epigenetic mechanisms of cancer development and progression, and clinical impact of functional variants. This position would require an individual to work under the direct supervision of a faculty member to develop software for scientific research. This position requires a working knowledge of one or more programming languages and software development techniques including. This position is affiliated with the Simons Center for Quantitative Biology ( SCQB ).Position RequirementsEDUCATION : Bachelor degree with at least one year of experience or Master degree in the quantitative sciences (Computer Science, Physics, Mathematics, Engineering etc.) EXPERIENCE & SKILLS : Required: work experience in C/C++ programming. Desired: experience in scientific data visualization (Python, Matlab, R), familiarity with genomics and the next-generation sequencing technologies. Applicant must be willing to relocate to Cold Spring Harbor Labs in Long Island NY. To be considered candidates must apply for this position via the CSHL website at: http://cshl.peopleadmin.com/postings/14571 Position Number 02263-R For more information about CSHL , please visit us at www.cshl.edu. Cold Spring Harbor Laboratory is a world-renowned research and educational institution with programs in cancer, neuroscience, plant biology, genomics and bioinformatics. The Laboratory is recognized internationally for its excellence in research and educational activities. We offer a competitive salary and a comprehensive benefits package. CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability or protected veteran status.PI107483745

Cold Spring Harbor LaboratoryRequisition InformationRequisition TitleComputational Science Developer IPosition CategoryScience/ResearchRequisition Number02263-ROpening InformationJob StatusFull TimeEducation RequiredUndergraduate DegreeExperience Required1 - 3 YearsPosition DescriptionCold Spring Harbor Laboratory invites applications for a Computational Science Developer I in the laboratory of Dr. Alexander Dobin. The successful candidates will join a team of biological data scientists working on novel statistical methods and computational algorithms for multi-omics processing and integration, and leverage Big Genomic Data to elucidate various problems in precision health, such as genetic and epigenetic mechanisms of cancer development and progression, and clinical impact of functional variants. This position would require an individual to work under the direct supervision of a faculty member to develop software for scientific research. This position requires a working knowledge of one or more programming languages and software development techniques including. This position is affiliated with the Simons Center for Quantitative Biology ( SCQB ).Position RequirementsEDUCATION : Bachelor degree with at least one year of experience or Master degree in the quantitative sciences (Computer Science, Physics, Mathematics, Engineering etc.) EXPERIENCE & SKILLS : Required: work experience in C/C++ programming. Desired: experience in scientific data visualization (Python, Matlab, R), familiarity with genomics and the next-generation sequencing technologies. Applicant must be willing to relocate to Cold Spring Harbor Labs in Long Island NY. To be considered candidates must apply for this position via the CSHL website at: http://cshl.peopleadmin.com/postings/14571 Position Number 02263-R For more information about CSHL , please visit us at www.cshl.edu. Cold Spring Harbor Laboratory is a world-renowned research and educational institution with programs in cancer, neuroscience, plant biology, genomics and bioinformatics. The Laboratory is recognized internationally for its excellence in research and educational activities. We offer a competitive salary and a comprehensive benefits package. CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability or protected veteran status.PI106641676

Cold Spring Harbor LaboratoryRequisition InformationRequisition TitlePostdoctoral FellowPosition CategoryScience/ResearchRequisition Number02279-ROpening InformationJob StatusFull TimeEducation RequiredNot IndicatedExperience RequiredNot IndicatedPosition DescriptionThe Sheltzer Lab at Cold Spring Harbor is seeking postdoctoral researchers for several projects studying the biology of cancer. Our laboratory is working to understand the genetic differences between normal, malignant, and metastatic cells. To that end, we are applying CRISPR mutagenesis, chromosome engineering, and single-cell sequencing to interrogate different types of cancer genetic alterations. We are particularly interested in using these technologies to model and characterize two types of alterations: 1) whole-chromosome aneuploidy and 2) druggable cancer dependencies. Our laboratory has pioneered new methods to analyze the role that gene dosage imbalances play in tumorigenesis (Sheltzer et al., 2017; Smith and Sheltzer, 2018). These approaches have furthered our understanding of the relationship between aneuploidy and cancer and have revealed multiple unexpected ways that these chromosomal alterations can affect tumor progression. We are seeking postdocs who are interested in using these approaches to uncover how aneuploidy and chromosomal instability can influence cancer initiation, drug resistance, and metastatic dissemination. We have also used CRISPR mutagenesis to dissect various cancer drug targets. Our research has revealed surprising discrepancies between the reported mechanisms-of-action of different anti-cancer agents and how these drugs actually work (Lin et al., 2017; Giuliano et al., 2018). We are seeking postdocs to apply cutting-edge CRISPR techniques to identify novel cancer dependencies and to discover the true targets of multiple cancer-killing drugs.Position RequirementsThe Sheltzer Lab is a highly-collaborative environment that values rigorous research and that welcomes scientists from all backgrounds. We are located at Cold Spring Harbor Laboratory, an immersive research institute on the outskirts of New York City. Cold Spring Harbor is an NCI -designated Cancer Center, and every year over 10,000 scientists journey to Cold Spring Harbor to attend one of CSHL's renowned Meetings and Courses. Please apply for this this position via the CSHL website at: http://cshl.peopleadmin.com/postings/14705 Position Number: 02279-R More information on research conducted in the Sheltzer Lab can be found on our website at: http://sheltzerlab.labsites.cshl.edu/. CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status. PI106592630

Cold Spring Harbor LaboratoryRequisition InformationRequisition TitleCollege Research InternPosition CategoryScience/ResearchRequisition Number02304-ROpening InformationJob StatusTemporaryEducation RequiredHigh SchoolExperience RequiredNonePosition DescriptionCold Spring Harbor Laboratory is currently seeking a college-level intern to work in the Computational Genomics laboratory of Dr. Alexander Dobin. The intern will join a team of biological data scientists working on novel statistical methods and computational algorithms for multi-omics processing and integration, and leverage Big Genomic Data to elucidate various problems in precision health, such as genetic and epigenetic mechanisms of cancer development and progression, and clinical impact of functional variants.Position RequirementsEDUCATION : College student enrolled in an undergraduate degree in biology, computer science molecular biology, genetics or related disciplines. Junior year is preferred. EXPERIENCE : Experience in scientific data analysis (C/C++, Python, Matlab, R), familiarity with genomics and the next-generation sequencing technologies. Strong interest in science and research. OTHER : Ability to work 20 - 35 hours/week in the summer. Must have reliable transportation . If interested, please apply for this position via the CSHL website at: http://cshl.peopleadmin.com/postings/14861 Position Number: 02304-R For more information about CSHL , please visit us at: www.cshl.edu CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status. VEVRAA Contractor.PI107369538

Cold Spring Harbor LaboratoryRequisition InformationRequisition TitleHistorianFunctional AreaLibraryRequisition Number00423-EOpening InformationJob StatusFull TimeEducation RequiredExperience RequiredPosition DescriptionThe Cold Spring Harbor Laboratory Archives, with the support of the Goelet Trust, seeks to fill a one-year Historian of Science position to appraise the historical collections of original materials in our archive. This position is instrumental in our preparations for the launch of the Center for Studies in Humanities and the Life Sciences at CSHL . The historian will thoroughly review and appraise the content of our extensive collections of original documents in enough detail to fully understand their scientific, historical, and social content. The historian will work systematically through collections, discover "hidden jewels" which will provide leads for future users of the collections in different disciplines and write short descriptions of items of special interest for dissemination purposes. All findings will be included in a detailed subject guide that the historian will begin in their first year at the Archives. Duties and Responsibilities: - Appraise the Archives' collections for their historical, cultural, and scientific importance, among other qualities - Expand our existing catalog with key words, subjects, and brief descriptions of the contents of the collections - Identify items of special interest, write brief descriptions of the item and its historical and scientific relevance for a lay audience, and post them on a blog maintained by the CSHL Archives - Generate a detailed study guide for the collections for use by future historians - Create a workshop at the end of the year together with the executive director of the library and archives - Present findings in papers at meetings/ workshop on history of sciencePosition RequirementsEducation: Ph.D. in History of Science is required. Experience: 2-3 years of experience in history of science fields is required. Preference will be given to candidates with a background in modern biology and especially to those who have experience in the history of the 20th century biology. Experience in writing for both general and scholarly audiences is required. Skills: Investigative and research skills. Analytical skills, the ability to analyze and interpret information. Excellent written and oral communication skills. Must have interests in scientific research in general and biology in particular. Please apply for the position via the CSHL careers website at: http://cshl.peopleadmin.com/postings/14852 Position Number 00423-E We offer a competitive salary and a comprehensive benefits package. The CSHL Archives ( http://library.cshl.edu/archives ) has been recognized consistently over the last three decades through substantial support from our institution, government agencies, foundations, and private donors for its programs and projects. Through this generous support, we have been able to preserve our collections, create exhibitions, initiate and successfully complete many digital projects, and develop outstanding educational and academic programs. The Archives houses a rich repository of rare books, manuscripts, correspondence, photographs, and scientific reprints documenting international genetics research since 1890. These materials provide deep insight into the history of molecular biology, genetics, and biotechnology. The Archives strives to develop novel ways of presenting and preserving the records of the discoveries in biomedical sciences as a topic of historical interest. We bring together important figures in the history of the molecular biology and genetics fields by collecting original materials that these individuals generated over their careers and conducting oral history interviews with them. As a result, we are able to merge discussions of the past and the future, thereby framing cutting-edge research in terms of detailed knowledge of the past. We are focused on creating a "living history" of important aspects of molecular biology and genetics research that blend the traditional discussions of current scientific research with lectures on the history of science; scholarly works; using our collections in public exhibitions; and scientific meetings in which the pioneers of the field interact with the current scientific community. For more information about CSHL , please visit us at www.cshl.edu. CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability or protected veteran status. VEVRAA Federal ContractorPI107343053

Cold Spring Harbor LaboratoryRequisition InformationRequisition TitlePostdoctoral FellowPosition CategoryPost DoctoralRequisition Number02266-ROpening InformationJob StatusFull TimeEducation RequiredGraduate DegreeExperience RequiredLess than 1 yearPosition DescriptionA joint postdoctoral position is available in the laboratories of Dr. Linda Van Aelst and Dr. Mikala Egeblad at Cold Spring Harbor Laboratories (www.cshl.edu). The main focus of the research project will be to study molecular determinants and biology of breast cancer and lung adenocarcinoma multi-organ metastasis by applying the latest RNAi/ CRISPR technologies and other genomic tools, as well as mouse models.Position RequirementsApplicants should have a Ph.D. in molecular biology, biochemistry, cell biology, or closely related areas. Experience in mammalian cell culture, basic molecular cloning, and basic biochemistry techniques is required. Experience in cancer biology, using animal models, and bioinformatics is highly desirable. A notable publication record, strong interpersonal, and teamwork skills are also required. Cold Spring Harbor Laboratory offers a highly collaborative social and scientific environment as well as a competitive salary and benefits in a beautiful location about one hour from New York City. If you are interested in joining the lab, please send a CV and a statement of your research accomplishments and interests along with the names of three references to: vanaelst@cshl.edu as well as submitting an online application here: http://cshl.peopleadmin.com/postings/14590 Position Number: 02266-R CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status. PI106514556

Cold Spring Harbor LaboratoryRequisition InformationRequisition TitleManager, Business SystemsPosition CategoryInformation TechnologyRequisition Number01267-AOpening InformationJob StatusFull TimeEducation RequiredUndergraduate DegreeExperience Required5 - 7 YearsPosition DescriptionCold Spring Harbor Laboratory ( CSHL ), located on Long Island, New York, is a private, not-for-profit research and education institution at the forefront of molecular biology and genetics. We are currently searching for a Business Systems Manager to join our Information Technology department. The ideal candidate will manage the deployment, maintenance, support and upgrade of business systems. In addition, the Manager will interact with all departments to identify and implement business systems initiatives, schedules, and document changes. Additional Responsibilities: - Effectively manage departmental resources, and staff, to complete tasks in a timely manner. - Manage, delegate, coach and train a staff of business systems analysts and business system administrators. - Create and maintain procedural documentation for the group, and assists in the creation of and adherence to IT policy. - Conduct periodic user meetings with departments and laboratory to gather and assess their business systems needs as well as informing them of significant changes. - Develop a yearly budget for the Business Systems group. - Oversee all upgrades and change management for the business systems. - Write proposals and work with vendors for the most advantageous quotes for projects. - Stay current with changes in the industry, and their ramifications to the organization. - Perform additional IT related tasks, as assigned by Director and Administration.Position RequirementsEducation Requirements: - Bachelor's degree in Computer Science or Business. - A degree or certificate in Computer Science. EXPERIENCE & SKILLS : - Previous experience in a Lawson/Infor enterprise environment. - More than seven years, combined, of previous business and IT experience. - More than three years in a management position within IT. - Strong interpersonal and communications skills - Familiarity with relational database concepts, and client-server concepts. - Capable of writing proposals or papers - Ability to act as a vender liaison - Ability to make presentations to organizational business units or professional peers - Ability to work closely with upper management - Ability to solve problems quickly and automate processes - Strong project management and resource management skills - Extensive experience in the areas of ERP , BI, HR, procurement, data warehousing. - Proven management skills - Able to adapt and influence in a rapidly changing environment, and possess excellent written and verbal communication skills. Please apply for the position via the CSHL careers website at: http://cshl.peopleadmin.com/postings/14611 Position Number 01267-A We offer a competitive salary and a comprehensive benefits package. Founded in 1890, CSHL has helped shape contemporary biomedical research and education with today's research endeavors encompassing cancer, neuroscience, plant biology and quantitative biology. CSHL is a private, not-for-profit institution in New York and has been home to eight Nobel Prize winners. Today, CSHL's multidisciplinary scientific community is bolstered by more than 600 researchers and its Scientific Meetings & Courses Program, which hosts more than 9,000 scientists from around the world each year on its campus. For more information about CSHL , please visit us at www.cshl.edu. & www.dnalc.org CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability or protected veteran status. PI106514593

Cold Spring Harbor LaboratoryRequisition InformationRequisition TitleAdministrative Course AidePosition CategoryAdministrative/ClericalRequisition Number01261-AOpening InformationJob StatusSeasonalEducation RequiredHigh SchoolExperience RequiredNonePosition DescriptionCold Spring Harbor Laboratory, a world-renowned research and educational institution located on the North Shore of Long Island, is seeking a summer Administrative Course Aide to provide administrative support to the Meetings and Courses office from mid-May through the end of August. The Administrative Course Aide will work a 40-hour week (9:00 a.m. to 5:00 p.m.) Monday through Friday. This is an entry level position and a great opportunity for college students looking to gain experience in an office setting, with a focus on grants management and accounting. Responsibilities: - data entry - preparing correspondence and reports - assisting in Grant preparation - filing - reviewing and processing travel vouchers - other duties as assignedPosition RequirementsEducation: College sophomore, junior or senior preferred. Experience: Some customer service and office experience a plus. Other requirements: Must have a clean, valid driver's license and use of a personal vehicle. Light lifting of boxes and is also required. If interested, please apply for this position via the CSHL website using this link: http://cshl.peopleadmin.com/postings/14595 Position Number: 01261-A For more information about CSHL , please visit us at www.cshl.edu. CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status. VEVRAA ContractorPI107266112

Cold Spring Harbor LaboratoryRequisition InformationRequisition TitleAdministrative Course AidePosition CategoryAdministrative/ClericalRequisition Number01261-AOpening InformationJob StatusSeasonalEducation RequiredHigh SchoolExperience RequiredNonePosition DescriptionCold Spring Harbor Laboratory, a world-renowned research and educational institution located on the North Shore of Long Island, is seeking a summer Administrative Course Aide to provide administrative support to the Meetings and Courses office from mid-May through the end of August. The Administrative Course Aide will work a 40-hour week (9:00 a.m. to 5:00 p.m.) Monday through Friday. This is an entry level position and a great opportunity for college students looking to gain experience in an office setting, with a focus on grants management and accounting. Responsibilities: - data entry - preparing correspondence and reports - assisting in Grant preparation - filing - reviewing and processing travel vouchers - other duties as assignedPosition RequirementsEducation: College sophomore, junior or senior preferred. Experience: Some customer service and office experience a plus. Other requirements: Must have a clean, valid driver's license and use of a personal vehicle. Light lifting of boxes and is also required. If interested, please apply for this position via the CSHL website using this link: http://cshl.peopleadmin.com/postings/14595 Position Number: 01261-A For more information about CSHL , please visit us at www.cshl.edu. CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status. VEVRAA ContractorPI106494294